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• have been told not to have sex, not to engage in sexual activity /actions that widen your blood vessels;
• have low blood pressure (hypotension);
• have had a stroke lately;
• have unstable angina;
• have had a heart attack; or
• have a history of non-arteritic anterior ischaemic optic neuropathy (this condition causes a sudden loss of vision).

side effects of pde-5 inhibitors include:

• men at risk of priapism, e.g. if you have sickle cell anaemia
• men using other erectile dysfunction medications
• men with a penile implant
• men who have been told to avoid sexual activity

men with the following conditions should not use alprostadil:

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